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Jewish Scientists: Block Memory of Alcohol Use and Cure the Habit?

Research teams headed by a Hebrew University graduate and Tel Aviv University researchers have suggested that an experiment on rats showed that blocking their memory of alcohol use helped them break the habit.

Memories of addiction often cause drinkers to return to their habit when they are aroused by the smell of alcohol, creating pattern difficult to break.

Dorit Ron, a neuroscientist at the University of California at San Francisco and a graduate of Hebrew University, led her team’s research that disrupted memories of rats that had been exposed to alcohol.

The scientists, along with a team from Tel Aviv University, identified a potential molecular target in the brains of rats that might be able to be used to help cure alcoholics.

Their study, published this week in Nature Neuroscience4, explained that rats became problem drinkers after spending seven weeks exposed to a choice of water or a mixture of water and 20% alcohol.

Ron said, “It’s pretty amazing. Over time, you can see they develop a strong preference for alcohol.”

The researchers then took the alcohol away from the rodents, but then gave them a drop a day of a liquid that had a slight taste and odor of alcohol. The rats that also received a drug to inhibit memory showed a lesser tendency to go back to the booze.

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