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November 21, 2014 / 28 Heshvan, 5775
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Posts Tagged ‘basis’

Israeli Scientists Find Way to Delay Cell Death

Thursday, July 12th, 2012

Israeli Researchers have discovered a protein that is central to delaying cell death, which “could lead to new approaches to treating cancer.”

The findings, led by Hebrew University graduate student Chen Hener-Katz and involving a collaboration between Prof. Assaf Friedler of the Hebrew University and Prof. Atan Gross of the Weizmann Institute, were published in the Journal of Biological Chemistry in an article titled ”Molecular Basis of the Interaction between Proapoptotic Truncated BID (tBID) Protein and Mitochondrial Carrier Homologue 2 (MTCH2) Protein.”

The discovery by Prof. Gross of the MTCH2 protein as well as its relationship to tBID, allowed the research team to develop a technique that mimics apoptosis.

Programmed cell death, or Apoptosis, is a critical defense mechanism against the development of abnormal cells like cancer, according to HealthCanal.com. “Cancer cells usually avoid this process due to mutations in the genes that encode the relevant proteins,” it continues. “The result is that the cancer cells survive and take over while healthy cells die.”

”These protein segments could be the basis of future anti-cancer therapies in cases where the mechanism of natural cell death is not working properly,” said Prof. Friedler, head of the school of chemistry at the Hebrew University. ”We have just begun to uncover the hidden potential in the interaction between these proteins. This is an important potential target for the development of anticancer drugs that will stimulate apoptosis by interfering with its regulation.”

The potential ramifications of this discovery was described in the Weizmann Institute’s 2010 Update on Cancer Research: “Scientists can use this newly gained knowledge to devise novel therapeutic methods. If clinicians could regulate the production and activity of MTCH2, they would be able, for instance, to ‘turn on’ mitochondria apoptosis in cancerous cells and turn it ‘off’ in the brain cells of patients with Parkinson’s and Alzheimer’s diseases.”

France Penalizes Boycott of Israeli Products

Thursday, July 12th, 2012

Last May, the Cour de Cassation, the Supreme Court of France, ruled that calls for a boycott of Israeli products constitute discrimination and as such are illegal under French law.

The verdict was the final ruling in a legal battle that went on for years. On 9 July 2005, exactly seven years ago, the Palestinian Authority called for a worldwide Boycott, Divestment and Sanctions (BDS) Campaign against the Jewish State. In February 2009, following the Gaza War in the winter of 2008-2009, several leftist and pro-Palestinian organizations in France convened to organize a French BDS campaign. The activists target French and international corporations that do business in Israel, French branches of Israeli companies, and supermarkets selling Israeli products.

Supermarkets are raided by commando units who block the entrances or storm the premises in order to remove the Israeli products or label them with stickers stating that Israel is an “apartheid state.” Often the raids are videotaped and posted on YouTube. The French revolutionary Left considers BDS to be a huge political success. The BDS actions attract a lot of support from Muslims youths from the suburbs surrounding the French cities. It is the first time since the 1960s and 70s that the French Left has been able to mobilize large numbers of youths.

BDS activists have succeeded in intimidating a number of supermarkets to remove Israeli products from their shelves, movie theaters to stop programming Israeli movies, and universities to cancel lectures by Israeli citizens. The lectures were boycotted simply because of their nationality and their Jewish religion; not for the opinions they personally might have held about Israeli politics.

Soon after the BDS raids began, the French Bureau National de Vigilance Contre l’Antisémitisme (National Bureau of Vigilance Against Anti-Semitism), a Jewish organization that was founded in 2002, started to lodge complaints against BDS at courts all over France. Sometimes the courts went along with the complaints, sometimes they did not.

In February 2010, the penal court of Bordeaux convicted Saquina Arnaud-Khimoun for labeling Israeli products with the sticker “Boycott Apartheid Israel.” The court ruled that she had “hindered the normal exercise of economic activities by making a distinction on the basis of nationality.” The French anti-discrimination act of 1981 prohibits “incitment to discrimination, hatred or violence against a person or a group of persons on the basis of descent, ethnicity and nationality or the fact whether or not one belongs to a race or a religion.” Arnaud-Khimoun was sentenced to a fine of €1,000 ($1,230). In October 2010, the Appeals Court of Bordeaux reaffirmed the verdict.

However, in July 2011, a court in Paris acquitted Olivia Zémor, a member of the group EuroPalestine, for posting a video on the internet showing Palestinian and French activists wearing t-shirts calling for a boycott of Israel. Zémor was brought to court by four organizations, including the Israeli Chamber of Commerce.

The Paris court ruled that calling for the boycott of Israeli products is not prohibited under French law. The tribunal said that “Criticism of a State or its policies cannot be regarded, in principle, as infringing the rights or dignity of its nationals, without seriously affecting freedom of expression in a world now globalized, whose civil society has become a major actor, and since no ‘criminal offence against a Foreign State’ has ever been established under substantive law or international common law, because this would be contrary to the commonly accepted standard of freedom to express opinions.”

The court added that “Since the call of a boycott of Israeli products is formulated by a citizen for political motives and is part of a political debate relating to the Israeli-Palestinian conflict – a debate concerned with a matter of general interest with international significance – the offence of incitement to discrimination, based on the fact of belonging to a Nation, is not constituted.” Moreover, the court pointed out, “certain sectors of Israeli opinion support the BDS call.” In this regard, it explicitly referred to the declaration of the Israeli Women’s Coalition for Peace.

The verdict in the Zémor case encouraged Arnaud-Khimoun in her decision to bring her case to the French Supreme Court. On 22 May, however, the French Cour de Cassation reaffirmed that publicly calling for the boycott of Israeli products is a case of incitement to discrimination on the basis of nationality.

Neytz HaChochma’s Unique Summer Camp

Thursday, June 21st, 2012

Children look forward to summer camp and Camp Neytz is a favorite with many who return year after year.

International food festivals each week, award-winning ceramic art creations, visits by a baby alligator, a giant toad and a talking parrot, and edible art creations each week are only part of the activities at Camp Neytz.

Kids all over North Miami Beach are envious of the camp’s monster water slide. Parents like knowing all meals and snacks are under strict kosher supervision. Field trips, sports and computer games are also part of the fun-filled summer at Camp Neytz.

The Neytz haChochma summer camp runs for six weeks, starting July 2. Camp Neytz is funded by The Children’s Trust, a dedicated source of revenue established by voter referendum to improve the lives of children and families in Miami-Dade County. There are 50 funded slots available on a first come, first served basis and they are filling fast. There is a minimal co-pay. Camp finishes on August 10th.

Neytz haChochma, a 12-year-old nonprofit Orthodox Jewish organization for Exceptional Student Education (ESE), operates a day school with a gifted cohort, an out-of-school program and the summer camp.

Applications are available for summer camp online at www.aaceschool.org, and may be submitted online or printed out and sent by mail.

Intimidation, Rebbes, Sages, Muslims, and the Proto-Apocalypse

Wednesday, May 23rd, 2012

My top pick for today is The Lid’s fascinating entry titled:

Convicted Terrorist Tries To Intimidate Blogger Stacy McCain Away From The Truth

It’s got everything, and if it’s real, then it’s pretty scary. So, let’s get scared together:

If you don’t know Robert Stacy McCain you are really missing something. As the saying goes, Stacy is a real trip. The Other McCain (he is the conservative one- unlike his distant cousin the Arizona senator) is no stranger to controversy mostly because of his honesty, he tells you exactly what he thinks.

I will tell you a secret about Stacy McCain that most people don’t know–if you need help –he will not only give you the shirt off his back but his back also.

Yesterday Stacy had to go into hiding. It stems from the fact he wrote a series of articles about convicted terrorist Brett Kimberlin, who now runs a 501(c) 3 organization, a Democratic party operative who is partially funded by progressive sugar daddy George Soros. The Lid

Just very good writing on a disputed Chasidic tradition:

Pilgrimage The eighteenth century polemic surrounding the emerging Chasidic movement took place on multiple levels, among them halakhic. One important anti-Chasidic disputant was R. Yechezkel Landau, whose scholarship was so massive that he continues to be a major force in Jewish law even two centuries later. A number of his halakhic rulings can be seen as disputing Chasidic practices, such as his responsum forbidding the recitation of a “Le-Shem Yichud” formula before performing a mitzvah. Another is his forbidding the common Chasidic practice of visiting one’s rebbe on holidays Hirhurim

Thought provoking entry:

New Old Torah A famous physician once passed through Bluzhov, and the Chassidim prevailed upon him to examine their rebbe. With some anticipation in his voice, the doctor told the Rebbe that he had detected a potentially serious heart flutter. Unimpressed, the Rebbe asked the physician, “ Do you know what today is?”

Not aware that the day was anything special at all, he admitted that he did not.

“Today is the 3rd of Sivan. In three days time, we will receive the Torah. How could my heart not flutter?”

He lived to the age of a hundred. Yitzchok Adlerstein, Cross-Currents

A little clunky, but worth following:

What have the Muslims ever done for us? Pirke De-Rabbi Eliezer is an Aggadah-midrash compiled in the first centuries of the Muslim occupation (7th-9th).  In chapter 30 we find a list of things the Muslims did in Israel.

“Woe to those who live in their [Muslim] days [...] The sons of Ishmael will do fifteen things in the Land at the end of days, and these are:

(1) They will measure the land with ropes, and (2) they will turn the cemetery into grazing lands and trash-heaps, and (3)they will measure from them (the cemeteries) and to the mountain-tops, and (4) lie will proliferate, and (5) truth will be persecuted [or: hidden], and (6) law will become distant from Israel, and (7) there will be many sins [or: poverty] in Israel. Ora, The Muqata

The three riders of the Proto-Apocalypse:

Violence, Peace and Hypocrisy It’s said and sung that “money makes the world go around,” but the grease that facilitates it IMHO is hypocrisy and anti-Semitism. Jews and Israel are always held up to obey rules that no other People, country or society ever need to worry about, and unfortunately it seems to never end.

There’s no rational, logical reason for people like myself, ordinary law-abiding people, Jews who live in Judea/Samaria to be condemned by international statesmen and media as “endangering” the peace while they coddle Iran trying to come up with all sorts of compromises to enable it to continue developing its nuclear industries, including weapons. Batya, Shiloh Musings

Do you like freaky and personal? Go for it:

Living in the Drawing I put on my bike helmet and coasted down our neighborhood hill to downtown, then across the Hawthorne Bridge on the municipally-designated bike lane, then pedalled easily in a middle gear up into Northeast Portland again via municipally-designated bike lanes.

Chronicles Of Crises In Our Communities

Thursday, May 10th, 2012

Dear Rachel,

As parents to a handful of boys, I’d say we have our hands full. Seriously, I realize that boys will be boys and I know we should be grateful that they’re not a bunch of sissies. But what we hadn’t counted on was our eldest – the supposedly mature one – endlessly picking fights with his younger brothers.

Rachel, I’m not talking about squabbles over something tangible; I mean unprovoked physical altercations, blows that hurt and lead to wailing and shrieks of pain by our younger children who honestly don’t ask for it.

This has been going on for quite some time now, and as nerve-wracking as the noise and mayhem have been, up until last week we just chalked it up to sibling rivalry, figuring that it had to do with the attention that was diverted from our oldest with each new addition to the family.

We’ve reasoned with Yonie (not his real name), tried charts with a reward system for good behavior, and even instituted special dates with mommy or daddy (where one child gets to enjoy the exclusive attention of one of his parents on an outing) on a rotating basis. Every time we think we’ve made progress, it’s back to square one a day or two later.

Like I said, until last week — when our son pounced on someone else’s child, a kid almost half his age. This was something new and something we weren’t going to tolerate.

That night we sat him down, determined to get to the bottom of what was driving our bechor –who, believe it or not, is otherwise a shy and soft-spoken soul – to act out in such bizarre fashion.

After endless prodding and seemingly getting nowhere, a question asked by his father led to the shocking revelation that our son was being hounded relentlessly by a school bully — on the school bus, on a daily basis, for almost two years now!! Further prompting brought to light that Yonie (of slight build) had a fear of his tormentor who was “much bigger than me.”

It began to dawn on us that our 12-year old son has been acting out his own frustration and “getting even” by pummeling his weaker younger brothers, and inadvertently teaching them all how to be bullies! My husband was also very concerned about Yonie’s lack of resilience in not standing up to the bully.

Hopefully, we will be able to reverse the damage that has been eating away at our boys. We’ve already been to the school to speak to the principal and will follow up to make sure that appropriate action is taken.

In the meanwhile, my message to parents is not to chalk up their child’s odd or out-of-character behavior to “a passing phase” or “sibling rivalry.” Get to the bottom of it — the sooner the better.

P.S. I don’t refer to a public school in Anytown, USA; our children attend a cheder in a baalbatish yeshivish community.

Still Shaken…

Dear Shaken,

Children in schools the world over are being affected by the scourge of bullying — so much so that there’s been a mound of research done to try and evaluate the extent, the causes and effects on both aggressor and victim, and the best course of action to take to protect our vulnerable children.

Bullying comes in the form of repeated physical, verbal or psychological assault, usually directed at victims who are unable to defend themselves. Now, this doesn’t mean that parents should suddenly consider their children’s quarrels among themselves or with their peers as bullying. A fight or argument, especially between equals in physical size and strength, doesn’t constitute bullying.

So what makes a child vulnerable and susceptible to being picked on this way? A whole host of things, in fact, such as a lack of verbal skills that impedes self-expression; the craving of attention; physical clumsiness; shyness; low self-esteem or even the lack of ability to build friendships.

If you’re wondering why your son never spoke to you or complained about the bullying, studies have shown that most victims don’t tell their parents or teachers for fear that they will not be believed and/or they feel that nothing will be done about it. Victims are also prone to fearing retaliation, as well as embarrassment, at being unable to stand up for themselves.

Your husband, by the way, may not be doing his son any favor by encouraging him to take on the bully. Without adult intervention, this can chas v’sholom end up causing Yonie physical harm.

In contrast to those parents who choose to look away when their children get involved in altercations with others outside their home, you did the right thing by taking your son to task about his unacceptable behavior. In addition, his low self-confidence will be boosted by your show of support and caring.

Chabad Of South Broward Holds Siyum

Thursday, May 10th, 2012

A siyum in honor of the conclusion of Seder Zeraim, the first of six orders of the Mishnah, was held on April 24, Iyar 2, at the Chabad of South Broward located in Hallandale Beach. The Mishnah is the basis of the Oral Torah. Zeraim deals primarily with agricultural laws.

Iyar 2, the date of the event, commemorates the birthday of Rabbi Shmuel Schneersohn, the fourth Lubavitcher Rebbe, known as the Rebbe Maharash (1834-1882). Iyar 2 also marked the day 17 years ago that the eleven months of Kaddish for the Lubavitcher Rebbe, Rabbi Menachem M Schneerson (1902-1994) was completed.

Every morning after the second minyan, a Mishnah is studied in the shul. Dubbed the “New York Mishnah,” this small daily class enables participants to fulfill the mitzvah, even if they’re rushing to work.

The study began three years ago, at first with five tractates. The first letter of the five tractates spelled out Yisroel, in memory of the late brother of Rabbi Raphael Tennenhaus, Rabbi Yisroel Tennenhaus, z”l. After the first five tractates were concluded, the study of Zeraim began.

Shas MK: All Israelis Should Serve Their Country

Wednesday, January 18th, 2012

Shas MK Rabbi Chaim Amsalem, writing in a column for the Jerusalem Post, lambasted UTJ MK Moshe Gafni for his “cynical declaration” that the ultra-Orthodox should not serve in the IDF.

Amsalem wrote that he was “confused and angered” by Gafni’s statements earlier in the week because they had “no basis in Jewish law or tradition, or in basic human ethics . . . they were nothing more than a continuation of extremist haredi policies and politics.”

Amsalem said that “Jewish tradition is replete with teachings regarding the responsibility we have toward one another,” and cited the Bible portion where Moses rebuked the tribes of Reuven and Gad for attempting to shirk combat in order to settle on the eastern side of the Jordan River.

Amsalem added: “I plan to continue encouraging haredim to serve in the IDF while working together with the army leadership to make sure all their needs are met.”

Printed from: http://www.jewishpress.com/news/breaking-news/shas-mk-all-israelis-should-serve-their-country/2012/01/18/

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