A few sources speculated that the explosion was the result of an Israeli air strike, but these were all unconfirmed.
Islamic State allegedly beheaded one American journalist, has threatened another with the same fate.
The Iranian-controlled media reported the bombing is "a message" to Israel.
Israel's PM Netanyahu is set to travel to Moscow next week to discuss the impact of Syria's crisis on Israel and the region.
Israeli fighter pilots again were sent to attack artillery positions in Syria in response to mortar fire aimed at the Golan Heights earlier in the day.
The Islamic State also takes control of a strategic and ancient city in Syria. Assad's army flees.
Another explanation to the Russians' decision to transfer the SU-57 to the Middle East might be their concern, even panic, over the US Air Force bombing of a Russian convoy which killed hundreds of mercenaries.
"No matter what you do to cut the route, the matter is over and the resistance possesses precision and non-precision rockets and weapons capabilities."
"Syria’s air defenses downed more than half of the Israeli missiles," Russia's Defense Ministry claimed.
The recent Israeli air strikes on Syria – which have neither been confirmed nor denied by Israeli officials – targeted weapons depots allegedly storing Iranian-made weapons intended for the Lebanese terrorist organization Hizbullah.
Hezbollah warns an IAF air strike on its convoy in Syria may lead to a "costly adventure."
Larijani urged Sunni Muslim countries to abandon their reliance on Israel and join up with Iran's war against the Zionist foe.
Rebels linked to Al-Qaeda have abducted Italian Jesuit Priest Paolo Dall’Oglio, a well-known advocate of Christian-Muslim dialogue and a vocal critic of the government...
'I think it's important that we remind ourselves that if good people don't band together then bad people can do a lot of damage in this world. '
"We condemn the insult our people have sustained in the liberated Al-Quneitra district in the form of food supplies awarded by the Zionist entity which is repressing the Golan which was sold out by the regime."
Downed Russian planes aside, Netanyahu said the primary reason for his talks with President Putin in Moscow is, as always, Iran.
Erdogan is sounding more like Assad and Mubarak every day. Protesters were vandals,. Now they are terrorists. He is making every mistake possible, fueling the protest movement by insulting it.
Obama jumps off the fence and will arm rebels. Military planners proposed a limited no-fly zone in Syria to help arm rebels. The US charges that Assad has killed more than 100 with chemical weapons.
President Trump is, in effect, ceding Syria, the Kurds, and, eventually, Iraq, to Russia and Iran. And he did it without consulting anyone in the Pentagon.
Residents of the area said at least four explosions were heard, adding there appeared to be an attack on an underground compound near the airport.
An elderly French Jew was among the dead in Wednesday's terror attack in Paris.
The sentences of three and four years are among the heaviest ever imposed in Israel for illegal association.
The new ISIS female commander is a Saudi woman who tweeted her intention to become a suicide bomber.
"The Iron Dome launch by the IDF came in response to the infiltration of an unidentified object," said the Golan Regional Council.
Secy Kerry is to meet with Jordan's FM Judeh and then King Abdullah II over the Syrian crisis and ISIS.